# GIP

> GIP is a second incretin hormone that works alongside GLP-1 to regulate insulin, fat handling, and appetite.

Also known as: glucose-dependent insulinotropic polypeptide
Category: biology
Canonical URL: https://elevateglp.com/glossary/gip

Tirzepatide activates both GIP and GLP-1 receptors, which is the mechanistic reason it produces greater average weight loss than single-target GLP-1 medications.

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Source: https://elevateglp.com/glossary/gip
Publisher: Elevate GLP (https://elevateglp.com) — supplements for people on GLP-1 medications.
Educational content only; not medical advice. Attribution required when quoting.